ZikaPLAN takes a comprehensive approach to tackling the Zika threat, encompassing epidemiological surveillance, clinical studies, the development of innovative diagnostic tools and control strategies, in addition to education and knowledge-sharing.

ZikaPLAN meeting Recife at work

Research groups in ZikaPLAN conduct clinical studies to investigate Zika’s connection with congenital syndromes and neurological complications, as well as the pathogenesis of severe cases. They explore non-vector and vector transmission and risk factors for geographic spread, measure the burden of disease and study how the virus has evolved, comparing current and historic strains.

To inform policy decisions, ZikaPLAN looks at novel personal preventive measures, innovation in diagnostics and modelling of vector control, as well as vaccine strategies.

The social sciences also play a role in ZikaPLAN, which aims to determine the best communication strategies to keep the affected communities informed.

ZikaPLAN works closely with two other European Union-funded consortia, ZIKAction and ZIKAlliance, to establish a Latin American and Caribbean network. This network will address the broader issue of building local capacity in Latin America to prepare for and rapidly launch a large-scale research response to emerging infectious disease threats. In this context, ZikaPLAN will contribute to developing an inter-epidemic research plan, policy recommendations, training, research networks and dissemination strategies that are designed to permanently strengthen local capacities, beyond the four years of the project. The three consortia have common bodies for the global management of scientific programs, communication, and ethical, regulatory and legal issues.

Working Groups

  1. MERG: Unravelling Congenital Zika Syndrome
  2. NEURO-ZIKA: Neurological Manifestations of Zika
  3. Non-vector Transmission of ZIKV
  4. NEURO-ZIKA: Pathogenesis
  5. Platform for Diagnostics Innovation and Evaluation
  6. INVADE: Investigating Vaccines in Antibody Dependent Enhancement
  7. Viral Fitness: Current Versus Historical ZIKV
  8. Disease Burden and Risk Assessment
  9. Mathematical Modelling to Inform Public Health Policies
  10. WEAR: Wearable Aedes Repellent Technologies
  11. ZIKA Collaborative Establishment of a Latin American Preparedness Network (PLAN)
  12. Dissemination and Communication
  13. Consortium Coordination
  14. Zika Data Share: Harmonisation of Data and a Roadmap Towards Data Sharing
  15. ZIKA-COLLAB: Intra-consortium Collaboration
ZikaPLAN Working Groups (WP)

ZikaPLAN Working Groups (WP)