Modelling an optimum vaccination strategy against ZIKA virus for outbreak use
Eduardo Massad et al. – Epidemiology & Infection, May 16, 2019
In this study, the authors present a model to optimise a vaccination campaign aiming to prevent or to curb a Zika virus outbreak. In particular, they aim to determine the optimum time point to introduce a mass vaccination campaign in response to an outbreak, the thresholds to declare an outbreak, the optimum duration of such a strategy and the coverage needed to avert an outbreak.
NEURO-ZIKA: Neurological Manifestations of Zika
Defining the spectrum of neurological diseases associated with Zika virus (ZIKV) infection, in both the central nervous system (CNS) and peripheral nervous system (PNS) of adults and children.
WEAR: Wearable Aedes Repellent Technologies
To protect pregnant women, novel, wash-in detergent formulations and long-lasting plastic technologies containing repellents for the treatment of clothing and other wearable repellent technologies are being developed using new microencapsulation techniques.
Investigating Vaccines in Antibody Dependent Enhancement
Identifying the major T-cell epitopes and cross reactive B-cell epitopes on ZIKV and assessing the role of flavivirus antibodies in protective and pathogenic immunity following ZIKV through antibody dependent enhancement (ADE).