Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations
Fabien Aubry et al. – Science, November 20, 2020
The findings in this report, an experimental comparison of wild populations of Ae. aegypti from different regions of the globe, provide an explanation to the lack of major Zika outbreaks in Africa until now. They also shed new light on the emergence of the virus and on the regional and continental differences in its public health impact.
NEURO-ZIKA: Neurological Manifestations of Zika
Defining the spectrum of neurological diseases associated with Zika virus (ZIKV) infection, in both the central nervous system (CNS) and peripheral nervous system (PNS) of adults and children.
WEAR: Wearable Aedes Repellent Technologies
To protect pregnant women, novel, wash-in detergent formulations and long-lasting plastic technologies containing repellents for the treatment of clothing and other wearable repellent technologies are being developed using new microencapsulation techniques.
Investigating Vaccines in Antibody Dependent Enhancement
Identifying the major T-cell epitopes and cross reactive B-cell epitopes on ZIKV and assessing the role of flavivirus antibodies in protective and pathogenic immunity following ZIKV through antibody dependent enhancement (ADE).