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Detection of Zika virus replication in human semen by reverse transcription polymerase chain reaction targeting of antisense RNA

Ralph Huit et al. – Journal of Infectious Diseases, February 13, 2020

In this article, the authors describe the results obtained from their RT-PCR assay that targets antisense ZIKV RNA (asRNA) to assess ZIKV replication competence in ZIKV RNA positive semen samples.

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Research Focus

NEURO-ZIKA: Neurological Manifestations of Zika

Defining the spectrum of neurological diseases associated with Zika virus (ZIKV) infection, in both the central nervous system (CNS) and peripheral nervous system (PNS) of adults and children.

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WEAR: Wearable Aedes Repellent Technologies

To protect pregnant women, novel, wash-in detergent formulations and long-lasting plastic technologies containing repellents for the treatment of clothing and other wearable repellent technologies are being developed using new microencapsulation techniques.

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Investigating Vaccines in Antibody Dependent Enhancement

Identifying the major T-cell epitopes and cross reactive B-cell epitopes on ZIKV and assessing the role of flavivirus antibodies in protective and pathogenic immunity following ZIKV through antibody dependent enhancement (ADE).

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