Authors’ commentary: Re-visiting the evolution, dispersal and epidemiology of Zika virus in Asia
Pettersson et al. – Emerging Microbes & Infections, May 2018
Zika virus (ZIKV) has attracted much attention globally, primarily because of its association with microcephaly in newborn babies, Guillain-Barre syndrome, acute disseminated encephalomyelitis in adults and transmission via the oral and sexual route. Much attention has been focused on the clinical symptoms, emergence, epidemiology and evolution of ZIKV in the Pacific region and the Americas. However, during 2016 and 2017, many new sequences were submitted from regions in Asia where there had been few previous reports of the presence of ZIKV.
NEURO-ZIKA: Neurological Manifestations of Zika
Defining the spectrum of neurological diseases associated with Zika virus (ZIKV) infection, in both the central nervous system (CNS) and peripheral nervous system (PNS) of adults and children.
WEAR: Wearable Aedes Repellent Technologies
To protect pregnant women, novel, wash-in detergent formulations and long-lasting plastic technologies containing repellents for the treatment of clothing and other wearable repellent technologies are being developed using new microencapsulation techniques.
Investigating Vaccines in Antibody Dependent Enhancement
Identifying the major T-cell epitopes and cross reactive B-cell epitopes on ZIKV and assessing the role of flavivirus antibodies in protective and pathogenic immunity following ZIKV through antibody dependent enhancement (ADE).