News

Explore the 5th Zika Cross-Consortia Newsletter!

May 28, 2019 - The 5th Cross-Consortia Newsletter features the latest advances and publications by the three Zika consortia. You will also learn about the launch of the European Clinical Research Alliance on Infectious Diseases (ECRAID), a new Zika vaccine ... Read more

Featured Publication

A peridomestic Aedes malayensis population in Singapore can transmit yellow fever virus

Elliott F. Miot et al. – PLOS Neglected Tropical Diseases, October 7th, 2019

In this study, the authors characterized the potential contribution of a mosquito species called Aedes malayensis to yellow fever virus transmission in Singapore. Aedes malayensis breeds in urban parks of Singapore and is suspected to have participated in the resurgence of other mosquito-borne diseases such as dengue because it is not targeted by current mosquito control measures. Not only was Ae. malayensis able to experimentally acquire and transmit yellow fever virus, but it was also found to engage in contact with humans in a field situation. This empirical evidence indicates that Ae. malayensis is a competent vector of yellow fever virus and should be targeted by mosquito control programs.

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Research Focus

NEURO-ZIKA: Neurological Manifestations of Zika

Defining the spectrum of neurological diseases associated with Zika virus (ZIKV) infection, in both the central nervous system (CNS) and peripheral nervous system (PNS) of adults and children.

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WEAR: Wearable Aedes Repellent Technologies

To protect pregnant women, novel, wash-in detergent formulations and long-lasting plastic technologies containing repellents for the treatment of clothing and other wearable repellent technologies are being developed using new microencapsulation techniques.

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Investigating Vaccines in Antibody Dependent Enhancement

Identifying the major T-cell epitopes and cross reactive B-cell epitopes on ZIKV and assessing the role of flavivirus antibodies in protective and pathogenic immunity following ZIKV through antibody dependent enhancement (ADE).

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